Academic Paper

Machine-learning algorithm to non-invasively detect diabetes and pre-diabetes from electrocardiogram

June, 2022

Abstract

Objectives 

Early detection is of crucial importance for prevention of type 2 diabetes and pre-diabetes. Diagnosis of these conditions relies on the oral glucose tolerance test and haemoglobin A1c estimation which are invasive and challenging for large-scale screening. We aimed to combine the non-invasive nature of ECG with the power of machine learning to detect diabetes and pre-diabetes.

Methods 

Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior

August, 2021

Highlights

  • UVB exposure increases circulating sex-steroid levels in mice and humans
  • UVB exposure enhances female attractiveness and receptiveness toward males
  • UVB exposure increases females’ estrus phase, HPG axis hormones, and follicle growth
  • Skin p53 regulates UVB-induced sexual behavior and ovarian physiological changes

Summary

Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs

August, 2022

Highlights

  • Advanced synthetic embryos (sEmbryos) self-assembled from ESCs in an ex utero setup
  • Naïve ESCs give rise to all embryonic and extra-embryonic compartments in sEmbryos
  • Post-gastrulation stem cell derived sEmbryos develop organ specific progenitors
  • Extra-embryonic compartments adequately develop in post-gastrulation whole sEmbryos

Summary

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