Planning a method for covariate adjustment in individually randomised trials: a practical guide
On 24 Apr, 2022 By admin 0 Comments
April, 2022
Abstract
Background
It has long been advised to account for baseline covariates in the analysis of confirmatory randomised trials, with the main statistical justifications being that this increases power and, when a randomisation scheme balanced covariates, permits a valid estimate of experimental error. There are various methods available to account for covariates but it is not clear how to choose among them.
Methods